Fort Worth, TX – (September 25, 2018) – Galderma Laboratories, L.P., a global leader focused on meeting the world’s increasing skin health needs, announced today that Restylane® Lyft will partner with celebrity manicurist Deborah Lippmann on the “Face Your Hands” campaign to educate women on the steps they can take to achieve more beautiful, younger-looking hands. The hands are one of the first areas of the body to show signs of aging¹, and can often appear years older than the face due to the appearance of prominent veins, bones, and tendons². Restylane Lyft is the first and only hyaluronic acid (HA) dermal filler FDA-approved to help reverse the signs of volume loss in aging hands.^3,4

Deborah Lippmann is one of the most sought after manicurists in the world and founder of her own line of luxury nail lacquers and hand care products. As part of the “Face Your Hands” initiative, Deborah Lippmann will connect with women across the country and share her coveted nail care and manicure tips along with her personal experience with Restylane Lyft for hands.

“As a nail expert, I take steps to keep my hands looking their best, including daily use of sunscreen and hand cream. However, no matter what I did, I felt like the skin on the back of my hands made me look older than my age,” said Deborah Lippmann. “I am so glad that Restylane Lyft is now FDA approved for the hands. I have used Restylane® dermal fillers for years to reduce the appearance of lines and wrinkles on my face, and I like the natural–looking results. Now I can help improve the appearance of my aging hands, and share my anti-aging hand care tips with others.”

Restylane Lyft was recently approved by the FDA for restoring age-related volume loss to the back of the hands³ . It is the first and only FDA approved injectable treatment for the hands that contains hyaluronic acid^3, 4, which is a naturally occurring substance that helps provide fullness and elasticity to the skin.

“Like Deborah Lippmann, many of my patients notice that their hands do not look as youthful as their faces, but they can’t pinpoint the reason. As you get older, the natural fat in the hands begins to deteriorate, and the underlying tendons and veins become more pronounced²,” stated New York City dermatologist Doris Day, M.D. “These are signs of volume loss which requires more than topical creams or lasers to treat. The ideal option is an injectable dermal filler like Restylane Lyft, the first and only HA filler for the hands. ^3,4

“We are very excited to be partnering with Deborah Lippmann to educate women about the steps they can take to achieve younger-looking hands,” said Alisa Lask, General Manager and Vice President of the U.S. Aesthetic Business at Galderma. “According to a recent survey conducted by Galderma, nearly 2 in 3 women (65 percent) age 40 and over think their hands make them look older than their age⁵. Now there is a safe, effective, dissolvable filler available to address aging hands, and complete an overall aesthetic look.”

*The Restylane Survey was conducted among 1,000 nationally representative U.S. women, ages 35+, between February 26 and March 5, 2018, using an email invitation and an online survey. The data points in this release represent data collected among women ages 40+ (N=741).

With over 30 million treatments worldwide and counting6, the Restylane® family of HA dermal fillers is the broadest portfolio of dermal fillers in the U.S. The portfolio of products help to smooth facial wrinkles and folds, such as smile lines (Restylane®-L, Restylane® Refyne, Restylane® Defyne and Restylane® Lyft with Lidocaine), create fuller and more accentuated lips (Restylane® Silk and Restylane®-L), and add lift and volume to the cheeks and the back of the hands (Restylane Lyft with Lidocaine).

To learn more about the Restylane family of products, visit www.RestylaneUSA.com, or follow RestylaneUSA on Facebook or Instagram.

About Galderma

Galderma, Nestlé Skin Health’s medical solutions business, was created in 1981 and is now present in over 100 countries with an extensive product portfolio to treat a range of dermatological conditions. The company partners with health care practitioners around the world to meet the skin health needs of people throughout their lifetime. Galderma is a leader in research and development of scientifically-defined and medically-proven solutions for the skin.

For more information, please visit www.galdermausa.com.

To earn exclusive rewards, bonuses and discounts on Galderma’s aesthetic treatments, join the ASPIRE Rewards program.

To learn more about ASPIRE, visit www.aspirerewards.com.

Contact

Shannon Iwaniuk

Corporate Communications,

Galderma

shannon.iwaniuk@galderma.com

Victoria Smurro

Marina Maher Communications

vsmurro@hellommc.com

212.485.6816

Important Safety Information

The Restylane family of products includes Restylane® , Restylane-L® , Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Refyne, and Restylane® Defyne.

APPROVED USES

Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips in patients over the age of 21.

Restylane® Lyft with Lidocaine is for deep implantation into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds and for cheek augmentation and for the correction of age-related midface contour deficiencies in patients over the age of 21.

Restylane® Silk is for lip augmentation and for correction of perioral wrinkles in patients over the age of 21.

Restylane® Refyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21.

Are there any reasons why I should not use products within the Restylane® family? (Contraindications)

To ensure a safe procedure, your doctor will talk to you about your medical history to determine if you are an appropriate candidate for treatment. You should not use products within the Restylane family if:

• You have severe allergies with a history of severe reactions (anaphylaxis)
• You are allergic to lidocaine or to any of the gram-positive bacterial proteins used to make hyaluronic acid
• You are prone to bleeding or have been diagnosed with a bleeding disorder

Restylane® Defyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe deep facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21.

Are there other precautions that I should discuss with my doctor?

• Tell your doctor if you are breastfeeding, pregnant, or trying to become pregnant. The safety of these products for use during pregnancy, or in women who are breastfeeding, has not been studied
• Restylane, Restylane-L, Restylane® Lyft with Lidocaine, Restylane Refyne and Restylane Defyne are intended to treat facial wrinkles and folds, such as nasolabial folds. Restylane and Restylane-L are also intended for lip enhancement. Treatments in other areas of the face have not been evaluated in clinical studies
• The safety and effectiveness of Restylane® Silk for areas other than the lips and perioral area have not been evaluated in clinical studies
• Tell your doctor if you have any history of scarring, particularly thick and stiff scars, or any pigmentation (skin color) disorders. These side effects can occur with hyaluronic acid fillers in general
• Tell your doctor if you are planning other laser treatments or a chemical peel, as there is a possible risk of inflammation at the treatment site if these procedures are performed after treatment
• Patients who experience skin injury near the site of injection with these products may be at a higher risk for side effects
• Tell your doctor if you are on any medications to decrease your body’s immune response (immunosuppressive therapy). Using these medications may increase your risk of bruising or bleeding at the gel injection site.
• Tell your doctor if you are using any “blood thinners” such as aspirin, warfarin, or any other medications that affect bleeding. Using these medications may increase your risk of bruising or bleeding at the gel injection site.
• The use of these products on gel injection sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete. Use of product in these areas could delay healing or make your skin problems worse.

What are the possible side effects?

The most commonly observed side effects are swelling, redness, pain, bruising, headache, tenderness, lump formation, and itching at the injection site. These are typically mild in severity and typically resolve in less than 7 days in nasolabial folds and less than 14 days in lips. Serious but rare side effects include delayed onset infections, recurrence of herpetic eruptions, and superficial necrosis at the injection site.

One of the risks with using this product is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin.

As with all skin injection procedures, there is a risk of infection. To report a side effect with any of the Restylane products, please call Galderma Laboratories, L.P at 1-855-425-8722.

The Restylane family of products is available only through a licensed practitioner.

Complete Instructions for Use are available at www.RestylaneUSA.com.

References:

¹Siamwala JH, Moossazadeh DG, et al. Aging decreases hand volume expansion with water immersion. Front Physiol. 2018 Feb;9(72): doi: 10.3389/fphys.2018.00072 2007:1-16.

²Fabi SG, Goldman MP. Hand rejuvenation: a review and our experience. Dermatol Surg. 2012 Jul;38(7 Pt 2):1112-27. doi: 10.1111/j.1524-4725.2011.02291.x.

³Restylane Lyft. Instructions for Use. Fort Worth, TX. Galderma Laboratories, L.P., 2018

⁴U.S. Food & Drug Administration. Recently Approved Devices - Restylane Lyft with Lidocaine - P040024/S099. https://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/DeviceApprovalsandCleara nces/Recently-ApprovedDevices/ucm609592.htm. Accessed July 29, 2018.

⁵Data on file. Restylane Survey Demographic Report (Wakefield Research), March 2018. 6Data on file. MA-31037 document. Fort Worth, TX: Galderma Laboratories, L.P., 2016.